DESCRIBE THE CHANGE OF PARAMETERS PAO2/FIO2, SPO2/FIO2 DURING TREATMENT AND TREATMENT RESULTS OF PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROMECAUSED (ARDS) CAUSED BY INFLUENZA A AT THE NATIONAL HOSPITAL OF TROPICAL DISEASES (2019 – 2021)

Trần Văn Giang1,, Trương Tư Thế Bảo1
1 Hanoi Medical University

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Abstract

Objective: Describe the change of parameters PaO2/FiO2, SPO2/FiO2 during treatment and treatment results of patients with Acute Respiratory Distress Syndromecaused (ARDS) caused by influenza A  at the National Hospital of Tropical Diseases (2019 – 2021). Materials and methodes: Cross-sectional description of 30 patients with Acute Respiratory Distress Syndromecaused (ARDS) caused by influenza A. Results: In the group of surviving patients, the PaO2/FiO2 index gradually increased during treatment, the increase was significant with p < 0.05. In the group of patients who died, the PaO2/FiO2 index tended to remain unchanged during treatment, the difference was not significant with p > 0.05. Pre-treatment PaO2/FiO2 and SPO2/FiO2 ratios are associated with mortality. The area under the curve (AUC) of PaO2/FiO2 was 0.625, the cut-off point was 90, the sensitivity and specificity of mortality prediction were 89% and 42%. The area under the curve (AUC) of SPO2/FiO2 was 0.727, the cut-off point was 116, and the sensitivity and specificity of mortality prediction were 89% and 58%. Overall mortality in the study was 40%.

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References

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