Article Sidebar

PDF
Date Published: 13/01/2022
Abstract Views: 690
Views PDF: 241
DOI: https://doi.org/10.51298/vmj.v509i2.1850
Issue
Vol. 509 No. 2 (2021)
Section
Các bài báo
How to Cite
Văn Giang, T. ., & Tư Thế Bảo, T. . (2022). DESCRIBE THE CHANGE OF PARAMETERS PAO2/FIO2, SPO2/FIO2 DURING TREATMENT AND TREATMENT RESULTS OF PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROMECAUSED (ARDS) CAUSED BY INFLUENZA A AT THE NATIONAL HOSPITAL OF TROPICAL DISEASES (2019 – 2021). Vietnam Medical Journal, 509(2). https://doi.org/10.51298/vmj.v509i2.1850

DESCRIBE THE CHANGE OF PARAMETERS PAO2/FIO2, SPO2/FIO2 DURING TREATMENT AND TREATMENT RESULTS OF PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROMECAUSED (ARDS) CAUSED BY INFLUENZA A AT THE NATIONAL HOSPITAL OF TROPICAL DISEASES (2019 – 2021)

Trần Văn Giang1,, Trương Tư Thế Bảo1
1 Hanoi Medical University

Main Article Content

Abstract

Objective: Describe the change of parameters PaO2/FiO2, SPO2/FiO2 during treatment and treatment results of patients with Acute Respiratory Distress Syndromecaused (ARDS) caused by influenza A  at the National Hospital of Tropical Diseases (2019 – 2021). Materials and methodes: Cross-sectional description of 30 patients with Acute Respiratory Distress Syndromecaused (ARDS) caused by influenza A. Results: In the group of surviving patients, the PaO2/FiO2 index gradually increased during treatment, the increase was significant with p < 0.05. In the group of patients who died, the PaO2/FiO2 index tended to remain unchanged during treatment, the difference was not significant with p > 0.05. Pre-treatment PaO2/FiO2 and SPO2/FiO2 ratios are associated with mortality. The area under the curve (AUC) of PaO2/FiO2 was 0.625, the cut-off point was 90, the sensitivity and specificity of mortality prediction were 89% and 42%. The area under the curve (AUC) of SPO2/FiO2 was 0.727, the cut-off point was 116, and the sensitivity and specificity of mortality prediction were 89% and 58%. Overall mortality in the study was 40%.

Article Details

Keywords

Acute Respiratory Distress Syndromecaused (ARDS), Influenza A

References

1. Mertz D, Kim T.H, Johnstone J, et al. (2013). Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis. Bmj. 347.
2. Task, F.A.D., Ranieri V.M, Rubenfeld G.D, et al. (2012). Acute respiratory distress syndrome. Jama. 307(23):2526-2533.
3. Troeger C.E, Blacker B.F, Khalil I.A, et al. (2019). Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017. The Lancet Respiratory Medicine. 7(1):69-89.
4. Lương Quốc Chính, Manabe T, Đỗ Ngọc Sơn, et al. (2019). Clinical epidemiology and mortality on patients with acute respiratory distress syndrome (ARDS) in Vietnam. PloS one. 14(8):e0221114.
5. Acute Respiratory Distress Syndrome Network. (2000). Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. New England Journal of Medicine. 342(18):1301-1308.
6. Meade M.O, Cook D.J, Guyatt G.H, et al. (2008). Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. Jama. 299(6):637-645.
7. Bellani G, Laffey J.G, Eddy F, et al. (2016). Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. Jama. 315(8):788-800.