NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ CHĂM SÓC TRẺ SƠ SINH NON THÁNG MẮC BỆNH MÀNG TRONG ĐƯỢC ĐIỀU TRỊ SURFACTANT TẠI BỆNH VIỆN PHỤ SẢN THÀNH PHỐ CẦN THƠ VÀ BỆNH VIỆN NHI ĐỒNG CẦN THƠ

Abstract

Background: hyaline membrane disease is a common problem in preterm infants. This disorder is caused primarily by deficiency of pulmonary surfactant in an immature lung. Surfactant administration for the treatment respiratory distress syndrome has been proven to be effective, safe and feasible and reduce mortality and complications. The care and follow-up after surfactant replacement are very necessary. Objectives: 1) To describe clinical of preterm infants with hyaline membrane disease was treated by surfactant replacement. 2) To evaluate the results of care for preterm infants with hyaline membrane disease was treated by surfactant replacement and some related factors. Materials and methods: a prospective study was conducted on 132 preterm infants diagnosed with respiratory distress syndrome was treated by surfactant replacement at the Can Tho Gynecology Obstetrics Hospital and Can Tho Pediatrics Hospital from 10/2020 - 06/2021. Results: the rate of male was 62.1%. The rate of gestation <32 weeks group was 79.6%. The rate of <1000 gram was 66.7%. There were 64,4% of patients having severe level of respiratory failure (Silverman score >5). The results of taking care of preterm infants after surfactant replacement were good at 81.1% and good at 18.9%. Relevant factors to the results of good taking care: gestation ≥28 weeks, birth weight ≥1500 gram, was treated by LISA method, infants having mild levels of respiratory failure, children without complications of atelectasis, pulmonary hemorrhage (p<0.05). Conclusion: the care and follow-up after surfactant replacement are very necessary.