TO COMPARE THE DEMAND FOR USEING MUSCLE RELAXAN IN LAPAROSCOPIC SURGERY IN GROUPS OF PATIENTS WITH OR WITHOUT HAD OBSERVED BY TOF WATCH

Phạm Quang Minh1,, Nguyễn Xuân Anh2
1 Hanoi Medical University
2 Bệnh viện Tai mũi họng trung ương

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Abstract

Laparoscopic surgery requires muscle relaxation to maintain the surgical field, stabilize the cardiovascular system, and ensure ventilation during inflation. In the past, muscle relaxants were used during induction as well as an adjunct to maintenance anesthesia period based on clinical experience and drug pharmacokinetics. The TOF Watch allows to assess the degree of muscle relaxation and guide to use drug supplementation based on objective parameters. We conducted a study to compare the demand for muscle relaxants in laparoscopic surgery in groups of patients with or without minitored by TOF Watch. Prospective study, randomized clinical intervention on 60 patients, divided into 2 groups, at Viet Duc Hospital from April to November, 2017. RESULTS: age, sex, ASA, operative time, and anesthesia time were similar in the two groups. There was no difference in the surgeon's assessment of the surgical status between the two groups. The group monitored by TOF Watch had less total muscle relaxant use during surgery compared with the group that was clinically monitored 45,327 ± 5,298 (mg) compared to 46,524 ± 5,386 (mg). The amount of muscle relaxant used in surgery by weight and time was also similar (0.216 ± 0.361 mg/kg/h versus 0.224 ± 0.362 mg/kg/h), the difference was not statistically significant with p > 0.05. Conclusion: patients who monitored by TOF Watch had less muscle relaxant used during laparoscopic surgery than the clinical monitoring group, but the difference was not statistically significant.

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